Sensitization to HY-Antigen in Female Donors Was Not Associated with the Post-Transplant HY-IgG Development Nor Clinical Outcomes in Sex-Mismatched Transplantation

"preparation of hy antibody in female mice as a model for sex preselection"

the aim of this sutdy is to prepare histocompatability y(hy) antibody in female mouse at the first phase (current study), and to separate mouse embryos with regard to their sex, to be able to obtain offsprings of disired sex, by means of hy antibody, at the second phase. totally 421 balb/c inbred mice were used. antibodies were produced in females by intraperitonial injections of spleen and tes...

HY peptides modulate transplantation responses to skin allografts.

Injection of female C57BL/6 mice with immature female bone marrow-derived dendritic cells (BMDC) pulsed with a single immunodominant HY(Db) Uty peptide, WMHHNMDLI, induces prolonged survival of syngeneic male skin grafts. In contrast, injection of immature female BMDC pulsed with a single MHC class I-restricted HY(Ab) Dby peptide, NAGFNSNRANSSRSS, causes immunization similar to that following i...

Transplantation tolerance induced by intranasal administration of HY peptides.

Induction of antigen-specific tolerance to transplantation antigens is desirable to control host-versus-graft and graft-versus-host reactions. Following molecular identification of a set of minor histocompatibility (H) antigens, we have used selected HY peptide epitopes for this purpose. Intranasal administration of individual major histocompatibility complex (MHC) class II-restricted HY peptid...

Identification of the Immunodominant HY

Dialogues and HY-arguments

This paper introduces a new class called hang yourself (HY) arguments into the theory of defeasible argumentation. The novelty of such arguments is that they are inherently destructive: they cannot be used to support conclusions but only to attack other arguments. In this paper it is described what these arguments are, how they can be formalized, and what the formal consequences are of adding t...